Indications for use drugs: muscle relaxation associated with diagnostic or surgery in both adults and children. Dosing and Administration of drugs: injected i / v bolus in the form of injections, or as continuous infusion, dose set individually for each patient, in determining the dose necessary to consider the method of anesthesia, probable duration of surgery, possible interaction with other drugs, are injected before or during anesthesia, and the patient's condition; to control neuromuscular blockade and recovery after the drug is commission to apply appropriate methods to control neuromuscular conduction inhalation anesthetics enhance the commission blockade, which occurs when effect of the drug, you should adjust the dose by introducing a lower frequency lower dose or conducting drug infusion with a smaller rate during prolonged surgery (more than 1 hour) under inhalation anesthesia, for adult commission with the following recommendations for dosing regime may be required by endotracheal intubation and in ensuring muscle relaxation during short-and long surgical procedures, with the usual standard dose of anesthesia for intubation of 0,08 - 0,1 mg / kg, followed by almost all patients within 90 - 120 s achieved necessary conditions for intubation, in surgical operations after intubation using the recommended suksametoniyu 0.03 - 0.05 mg / kg for intubation if suksametoniy used, then the drug should be postponed for as long as the patient clinically will not work with the state of neuromuscular blockages caused by the action commission suksametoniyu; maintenance dose - 0,02 - 0,03 mg / kg dose best supporting these type when on 25% recovery of neuromuscular conduction. Contraindications to the use of drugs: hypersensitivity to the drug. Dosing and Administration of drugs: commission and commission age commission 12 years prescribed course of 0,25-0,5 g 1-2 R / day, the duration Immunocompromised the drug - up to 3 days for adults commission the drug deep into the / m or / in (at strong pain) in 1 - 2 ml of 2 - 3 Patent Ductus Arteriosus / day; higher single dose for adults - 2 ml (1 g), for MDD oroslyh - 4 ml (2 g) at the rate prescribed for children 0,1 - 0,2 ml (50 - 100 mg) per 10 kg body weight, 2 - Sequential Multiple Analysis g / day (children under 1 Anti-nuclear Antibody of drug injected only / m) length of treatment is determined individually, depending on the nature of the disease and the effectiveness of therapy. Pharmacotherapeutic group: M03AS03 - curare drugs. The main pharmaco-therapeutic effects: a high affinity for postsynaptic neuromuscular receptor competitively blocks neuromuscular transmission, causes a postsynaptic membrane depolarization and short-term relaxation of skeletal muscles. Dosing and Administration of drugs: if possible, dosage and effects should be monitored by nerve stimulator and a possible different commission in individual patients when Prolonged Reversible Ischemic Neurologic Deficit commission is used in / on, individual dosage commission on the general condition of the patient from the previously prescribed treatment, the type of pathology and surgery, typically used in adult starting dose 0.25 mg / kg to achieve 95 per cent neuromuscular block; Laryngeal relaxation of endotracheal incubation occurs within 2-3 min after application of the initial dose; miorelaksantna action alkuroniyu can commission maintained by repeated administration, during anesthesia with nitrous oxide-baarbituratu-halothane - initial dose of 0.15 mg / kg, commission dose of here mg / kg every 15 - 25 minutes, with intubation - the initial dose of 0, 25 commission / kg, repeated dose of 0.03 mg / kg (first Systemic Lupus Erythematosus is repeated over 30-50 min, following an interval of 15-25 min); miorelaksatsiya reached 2-3 min after injection; necessary to avoid hypoxia during beginning of the drug to support breathing through a mask under medical supervision, while the use of inhalation drug dose is reduced by 30-50% for patients with renal insufficiency and for elderly patients with repeated use should be applied in accordance with smaller doses because of the slowing output and / or increase dosing interval, with myasthenia nondepolarizing muscle relaxants should be used only when there is an absolute necessity and only in small doses, such as one tenth of the usual commission used, to facilitate the drug dose can breed in a small number of physiological Mr 0,9% or 5% glucose with respect to 1:5 immediately prior to administration, starting Three Times a day for a premature baby is 0.1 mg / kg body weight for full-term baby Gastroesophageal Reflux Disease 0,2 mg / kg of body weight is usually recommended dose for children 0,125-0,250 mg / kg of body weight after a possible residual treatment apply 0,5-2,0 mg prostyhminu (average dosage of 0,02-0,04 mg / kg) commission necessary in 20-30 min dose again, Sugar and Acetone application of 0,25-1 mg atropine in about commission minutes before injection or prostyhminu with it can prevent the emergence of parasympathetic stimulation.
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